YOUNG ONSET OF DM WITH UNCONTROLLED SUGARS WITH GENERALIZED WEAKNESS OF BOTH UPPER AND LOWER LIMBS

YOUNG ONSET OF DM WITH UNCONTROLLED SUGARS WITH GENERALIZED WEAKNESS OF BOTH UPPER AND LOWER LIMBS



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                                         " I’ve been given this case to solve in an attempt to understand the topic of “patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations, and come up with diagnosis and treatment plan "


Unit posting (Intern 2017)

Medical Ward 
GM II 
Dr Nikitha
Dr Pavan
Dr Lohith
Dr Stimita



Chief complaints 

25 years old male patient  came to OPD with a complaint of generalised 

weakness of upper and lower limb since 2-3 months.



HOPI

patient was apparently asymptomatic 3 months ago,then he developed 

polyuria, nocturia and generalised weakness and visited local hospital and after 

getting all Investigations done,he was diagnosed with type 2 diabetes mellitus and 

on regular medication (medication not known)

H/o ployphagia, polydypsia.

No h/o burning  micturition. 

H/o tingling sensation  of feet since 2-3 months(no numbness)

H/o headache on and off ,diffuse, throbbing type and relieves on taking medication.

No h/o photophobia, phonophobia.

History of neck pain on and off

H/o SOB on lying down after having food and relieves on sitting position since 3 months.

H/o weight loss (2-3 kgs in 3 months)




Past history 

No history of Hypertension, Bronchial Asthma, Epilepsy, thyroid 

,tuberculosis ,CVA,CAD



Family history 

His father is diabetic  since 5 years.



Personal history 

He is 25 years old and driver by occupation.He stays with his parents.His basically  

leads a sedentary  lifestyle  because of his occupation, and  there is no physical 

exercise in his daily routine. He wakes up in the morning  around  7-7:30 am then 

takes his breakfast(usual south Indian breakfast  e.g idli,vada)and goes for his 

occupation.He takes his lunch when he gets time(between 1-3 pm), lunch and dinner 

also are usual south Indian dishes(rice,dal,sambar). When I kept on asking , he 

mentioned  that he eats less vegetables  and likes to eat more chicken, mutton, fish, 

oily spicy fatty  food(fast food) and never thought  of controlling junk food.He doesn't  

smoke but occasionally  drinks with friends.



But now when we explained about his health condition,consequences of continuing 

his diet pattern and sedentary lifestyle, he said that he will change his diet and 

lifestyle. 

In short,
He takes mixed diet
Appetite normal
Bowel and bladder movements are regular 
Non smoker
Occasional alcoholic
No known allergies


General examination 

Well informed consent is taken. Examined in a well lit room.

Patient is conscious coherent and coperative well oriented to time place and person.

Moderately built and moderately Nourished. 

Vitals 

Afebrile
BP 110/80mmhg
PR 84bpm
Respiratory rate 18 cpm


 There  is no icterus, clubbing, cyanosis or lympathadenopathy,Pedal Edema 







Systemic examination 

Abdominal examination 

INSPECTION:

•Shape – scaphoid
Flanks – free
Umbilicus –central in position , inverted.
All quadrants of abdomen are moving equally with respiration.
No dilated veins, hernial orifices, sinuses
No visible pulsations.

 PALPATION:

•No local rise of temperature and tenderness
All inspectory findings are confirmed.
No guarding, rigidity
Deep palpation- no organomegaly.

 PERCUSSION:

•There is no fluid thrill , shifting dullness.
Percussion over abdomen- 
tympanic note heard.

 AUSCULTATION:

 Bowel sounds are heard.

Cardiovascular system examination 

INSPECTION:

•Chest wall - bilaterally symmetrical 
No dilated veins, scars, sinuses

PALPATION:

•Apical impulse is felt on the left 5th intercostal space 1cm medial to mid clavicular line.
No parasternal heave, thrills felt

 AUSCULTATION:

•S1 and S2 heard , no added thrills and murmurs heard.

 Respiratory system examination 

INSPECTION:

•Chest is bilaterally symmetrical
Trachea – midline in position.0
Apical Impulse is not appreciated 
Chest is moving normally with respiration.
No dilated veins, scars, sinuses.

PALPATION:

•Trachea – midline in position.
Apical impulse is felt on the left 5th intercoastal space.
Chest is moving equally on respiration on both sides
Tactile Vocal fremitus - appreciated 

 PERCUSSION:

The following areas were percussed on either sides- 

Supraclavicular-resonant
Infraclavicular- resonant
Mammary- resonant
Axillary- resonant
Infraaxillary- resonant
Suprascapular- resonant 
Infrascapular- resonant 
 interscapular - resonant.

 AUSCULTATION:

•Normal vesicular breath sounds heard 
No adventitious sounds 



CNS EXAMINATION:

HIGHER MENTAL FUNCTIONS:

Oriented to time place and person 

Immediate memory:Intact

Short term memory:Intact

Longterm memory:Intact

No delusions and hallucinations.



CRANIAL NERVES:

-Olfactory nerve(I): Smell is intact 

-Optic nerve(II):size of both pupils equal.

Pupil reactivity to light:present 

Direct and indirect light reflex are present in both eyes.

-Oculomotor(III),Trochlear(IV)and Abducens(VI):ocular movements present.No 

diplopia,No ptosis,No Horizontal Nystagmus

-Trigeminal(V): Sensations over the face present.

Corneal reflex:present 

Jaw jerk: present

Muscles of mastication:Normal(No wasting)

-Facial nerve(VII): No deviation of mouth

The wrinkles on both sides of forehead are present.

Taste:intact.

Secretions:Normal in eyes.

-Vestibulocochlear nerve(VIII):Hearing intact.

No positional vertigo and nystagmus.

-Glossipharyngeal (IX) and Vagus(X): uvula is centre and pilatoglossus pillars are 

normal and gag reflex intact.

Taste sensations from posterior tongue is normal.

-Spinal accesory(XI):Trapezius and Sternocleidomastoid normal.

-Hypoglossal(XII): Tongue (opening )central in postion.

No weakness and wasting of tongue.
Tongue moments normal.

MOTOR SYSTEM:

No visible muscle wasting is seen on inspection.

TONE OF THE MUSCLE:

Right: upper limb—Normal tone
           lower limb—Normal tone

Left:Upper limb—-Normal tone
        lower limb—-Norma tone.

POWER OF MUSCLE:

Right upper limb: 5/5

(Tested for supraspinatus,Deltoid,infraspinatus,Rhomboid,pectoralis major,latissimus dorsi,biceps, brachioradialus, triceps,Extensor carpi radialis, Extensor carpi ulnaris,Extensor digitorum,Flexor carpi radialis and Flexor carpi ulnaris,Abductor pollicis longus, Extensor pollicis brevis,Extensor pollicis longus,Lumbricals,Abductor digiti minimi.)

Right lower limb:5/5

(Tested for Quadriceps femoris,Tibialis anterior,Tibialis posterior,Gastrocnemius,peronei,Extensor digitorum longus,flexor digitorum longus,extensor digitorum brevis,extensor hallucis longus)
Left upper limb:5/5
Left lower limb:5/5

POSTURE AND GAIT: 

No abnormal  seen.
No involuntary movements or tremors are seen.

Reflexes        Right        Left

   Biceps.        Absent.    Absent 

   Triceps             ++              ++

  Supinator.         ++.             ++

   Knee.                ++.             ++

   Ankle.               ++.             ++

   Plantar.           Mute.        Mute


SENSORY SYSTEM:

Spinothalamic

1. Crude touch-present 
2.pain-present
3.temperature -present

Posterior  column

1.fine touch-+
2.vibration
Olecranon process -N
Styloid process-N
Shaft of tibia-N
Medical malleolus

Cortical

1.graphethesia-+
2.stereognosis-+
3.tactile stimulation -+



Cerebellar function tests:

No ataxia
No dysarthria,tremors,hypotonia
 
Coordination tests:

Finger nose test: done by both hands(normal).
No overshooting.
Finger to finger testing:no incordination.
Diadokokinesia: normal
Heel knee test: no incordination
Steriognosis : intact

Autonomic nervous system:
No increased sweatin
No postural hypotension

Meningeal signs:
No neck pain
No spinal and cranial abnormalities 
No carotid bruit


INVESTIGATION

CUE (12/6/23)

CBP(12/6/23)

FBS(12/6/23)
PLBS(12/6/23)


LFT(12/6/23)

TB-3.78
DB-1.85



RFT(12/6/23)


LIPID PROFILE (12/6/23)


HEMOGRAM(13/6/23)

ECG(13/6/23)


CHEST X RAY (13/6/23)



2d ECHO(15/6/23)


DIAGNOSIS

uncontrolled sugars with young onset of diabetes under evaluation with hypertryglyceridemia with hyperbiliribinemia



TREATMENT


1. Inj. HAI according to GRBS SC/TID (PRE MEAL)
2.Inj. NPH SC/BD 
3. Tab. FENOFIBRATE  160 mg PO/OD 
We started  this Treatment  in our hospital  after admission and  7 point  grabs profiles were observed. 


So we took Endocrinology opinion on 16/6/23 

And he was advised  to take
1. Strict diabetic  diet


2.15 units of regular  insulin s/c premeal(5units -5 units -5 units) and
 15 units of NPH(8units- × -7units) everyday

Total 30 units of insulin everyday.


3. And was advised to get one USG abdomen done for his hypertriglyceridemia (which may lead to pancreatitis)-pancreas was normal in size and echotexture


And for his hypertriglyceridemia ,

Gastroenterology  opinion  was taken on 16/6/23.

 Our Gastroenterologist suspected  mild hepatitis (but his serology reports were negative)
and he was advised  to take
1.Tab. BILYPSA 4mg (saroglitazar) once a day.


We took ophthalmology opinion 

but on examination, in both the eyes NO changes  of diabetic  retinopathy noted.
 

So while discharging  we advised him to take-

1. Strict diabetic  diet
2.15 units of regular  insulin s/c premeal(5units -5 units -5 units) and
 15 units of NPH(8units- × -7units) everyday
3.Tab. BILYPSA 4mg (saroglitazar) once a day.
And he was advised  to review  after 1 week  on our opd.

                                      








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